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Aspirin is the most widely used drug in the world. It has even been recognized as such by the Guinness Book of World Records.
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Your heart beats over 36 million times a year.
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Excessive alcohol use costs the country approximately $235 billion every year.
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Side effects from substance abuse include nausea, dehydration, reduced productivitiy, and dependence. Though these effects usually worsen over time, the constant need for the substance often overcomes rational thinking.
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Coca-Cola originally used coca leaves and caffeine from the African kola nut. It was advertised as a therapeutic agent and "pickerupper." Eventually, its formulation was changed, and the coca leaves were removed because of the effects of regulation on cocaine-related products.