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Vaccines prevent between 2.5 and 4 million deaths every year.
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Drug-induced pharmacodynamic effects manifested in older adults include drug-induced renal toxicity, which can be a major factor when these adults are experiencing other kidney problems.
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An identified risk factor for osteoporosis is the intake of excessive amounts of vitamin A. Dietary intake of approximately double the recommended daily amount of vitamin A, by women, has been shown to reduce bone mineral density and increase the chances for hip fractures compared with women who consumed the recommended daily amount (or less) of vitamin A.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.