An 8-week-old is diagnosed with a congenital heart disease and ...

[SO00]

An 8-week-old is diagnosed with a congenital heart disease and Down syndrome. The infant is at risk for the development of which gastrointestinal disorder?
 
  a. Intussusception
  b. Imperforate anus
  c. Meckel diverticulum
  d. Cystic fibrosis (CF)

Question 2

A 2-month-old is diagnosed with Hirschsprung disease with the resulting development of a megacolon. What is the most likely cause of this condition?
 
  a. Absence of intrinsic ganglion cells result-ing in impaired peristalsis
  b. The use of cow's milk instead of formula
  c. Excessive use of glycerin suppositories to promote bowel elimination
  d. Additional ganglion cells throughout the length of the colon

[tofugiraffe]

Answer to Question 1

ANS: B
Approximately 40 of infants with anorectal malformations have other developmental anomalies (i.e., Down syndrome, Hirschsprung disease, and duodenal atresia). The risk is not present for intussusception, Meckel diverticulum, or cystic fibrosis.

Answer to Question 2

ANS: A
Congenital aganglionic megacolon is caused by the absence of the intrinsic ganglion cells (sub-mucosal and myentric plexuses) along a variable length of the colon, resulting in inadequate peri-staltic movement in the bowels. The resulting distention of the proximal colon results in the term megacolon. Megacolon is a functional anatomic disorder not related to formula or use of suppos-itories.

[SO00]

Thanks for the timely response, appreciate it

[bigsis44]

Excellent