A 3-year-old is making play cakes in a sandbox and is eating the ...

[Evvie72]

A 3-year-old is making play cakes in a sandbox and is eating the play cakes. The sand was also being used by cats as a litter box and was contaminated with toxoplasmosis. Which of the fol-lowing would most likely also be present?
 
  a. Granuloma formation
  b. Degranulation
  c. Blood clots
  d. Exudate production

Question 2

The macrophage secretion that stimulates procollagen synthesis and secretion is:
 
  a. angiogenesis factor.
  b. matrix metalloproteinase.
  c. vascular endothelial growth factor.
  d. transforming growth factor-beta.

[enass]

Answer to Question 1

ANS: A
Infections caused by bacteria such as toxoplasmosis can result in granuloma formation. Degranu-lation is a part of mast cell destruction. Blood clots are not expected with chronic inflammation. Exudate production is pus formation.

Answer to Question 2

ANS: D
Macrophages secrete transforming growth factor-beta to stimulate fibroblasts to secrete the col-lagen precursor procollagen. Angiogenesis factor supports the growth of new vessels. Matrix metalloproteinase remodels proteins at the site of injury. Vascular endothelial growth factors are also involved in vessel growth.