A 40-year-old male client is shocked to receive a diagnosis of ...

[Kikoku]

A 40-year-old male client is shocked to receive a diagnosis of mature B-cell lymphoma and is doing research on his diagnosis on the Internet.
 
  Which of the following statements that he reads on various Web sites is most reliable?
  A)
  Like most forms of Hodgkin lymphoma, mature B-cell lymphoma often requires radiation treatment.
  B)
  Doctors are able to diagnose mature B-cell lymphoma by the presence of Reed-Sternberg cells.
  C)
  Unlike many other lymphomas, mature B-cell lymphoma is often self-limiting, and treatment is focused on symptoms.
  D)
  The lymph nodes are usually affected, and often the spleen and bone marrow.

Question 2

A 14-year-old boy has been diagnosed with infectious mononucleosis. Which of the following pathophysiological phenomena is most responsible for his symptoms?
 
  A)
  The Epstein-Barr virus (EBV) is lysing many of the boy's neutrophils.
  B)
  Viruses are killing some of his B cells and becoming incorporated into the genome of others.
  C)
  The EBV inhibits the maturation of white cells within his peripheral lymph nodes.
  D)
  The virus responsible for mononucleosis inhibits the maturation of myeloblasts into promyelocytes.

[SeanoH09]

Answer to Question 1

Ans:
D

Feedback:

The NHL subtypes of mature B-cell lymphoma may affect the lymph nodes, spleen, or bone marrow. It is not a type of Hodgkin lymphoma, and Reed-Sternberg cells would indicate Hodgkin lymphoma. It is not self-limiting and necessitates active treatment.

Answer to Question 2

Ans:
B

Feedback:

B lymphocytes all of which have receptors for the EBV that causes mononucleosis. Infection of the B cells may take one of two formsit may kill the infected B cell, or it may become incorporated into its genome. Lysis of neutrophils or inhibition of white cell maturation or differentiation is not a central component of mononucleosis etiology.

[Kikoku]

Thanks for the timely response, appreciate it

[kusterl]

TYSM