A 37-year-old male with HIV who has recently become symptomatic ...

[eruditmonkey@yahoo.com]

A 37-year-old male with HIV who has recently become symptomatic has begun highly active antiretroviral therapy (HAART).
 
  Among the numerous medications that the man now regularly takes are several that inhibit the change of HIV RNA to DNA in a CD4+ cell. Which of the following classes of medications addresses this component of the HIV replication cycle?
  A)
  Entry inhibitors
  B)
  Protease inhibitors
  C)
  Integrase inhibitors
  D)
  Non-nucleoside reverse transcriptase inhibitors

Question 2

A newly diagnosed HIV-positive adolescent has blood work drawn, which includes a CD8 T-cell count. The nurse knows which of the following functions of CD8 T cells listed below will assist the adolescent's immune system in fighting off the viral attack? Se
 
  A)
  Release destructive enzymes
  B)
  Trigger intracellular programmed death
  C)
  Cause allergens to surround the virus
  D)
  Boost antigen-antibody response
  E)
  Remove foreign material from lymph before it enters the blood

[ultraflyy23]

Answer to Question 1

Ans:
D

Feedback:

Reverse transcriptase inhibitors inhibit HIV replication by acting on the enzyme reverse transcriptase. Non-nucleotide reverse transcriptase inhibitors block the copying of RNA into DNA. Entry inhibitors, protease inhibitors, and integrase inhibitors do not address this aspect of the HIV replication cycle.

Answer to Question 2

Ans:
A, B

Feedback:

The primary function of cytotoxic T (CD8) cells is to monitor the activity of all cells in the body and destroy any that threaten the integrity of the body. The CD8 cells destroy target cells by releasing cytolytic enzymes, toxic cytokines, and pore-forming molecules or by triggering membrane molecules and intercellular apoptosis. Removal of foreign material from lymph before it enters the blood is the function of lymph nodes.