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Human kidneys will clean about 1 million gallons of blood in an average lifetime.
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By definition, when a medication is administered intravenously, its bioavailability is 100%.
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The first war in which wide-scale use of anesthetics occurred was the Civil War, and 80% of all wounds were in the extremities.
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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
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Vaccines prevent between 2.5 and 4 million deaths every year.