What plasma protein is important for normal wound healing and ...

[jayhills49]

What plasma protein is important for normal wound healing and stabilization of the fibrin clot?
 
  a. Tissue factor
  b. Prothrombin
  c. Factor Xa
  d. Factor XIIIa

Question 2

Which of the following therapies actually lyses the clot rather than prevents future clots?
 
  a. Aspirin
  b. Heparin
  c. TPA
  d. Coumadin

[yasmin]

Answer to Question 1

ANS: D
Factor XIIIa stabilizes the fibrin polymer and is essential for normal wound healing, as well as tissue integrity.

Answer to Question 2

ANS: C
TPA is normally released from endothelial cells and activates plasminogen, which then gradually lyses the fibrin clot. TPA is used therapeutically to lyse pathologic clots in thrombotic disease. Aspirin inhibits platelet function, heparin binds to antithrombin to inhibit thrombin, and Coumadin interferes with normal synthesis of the vitamin Kdependent proteins.