Author Question: Iron overload in severe b-thalassemia (b-thalassemia major) patients is primarily a consequence of: ... (Read 27 times)

saliriagwu · **on:** Jun 25, 2018

Iron overload in severe b-thalassemia (b-thalassemia major) patients is primarily a consequence of:

a. An increased rate of absorption of iron because of the severe anemia
b. A decreased need for iron because fewer RBCs are made
c. Accumulation of iron from massive RBC transfusion therapy
d. Decreased rate of use of iron because smaller RBCs are made

Question 2

A chemotherapy patient's white blood cell (WBC) count is 1.0 109 /L. There are 60 segmented neutrophils, 38 lymphocytes, and 2 monocytes. What is the correct interpretation of the relative differential?

a. Normal
b. Neutrophilia
c. Neutropenia
d. Lymphopenia

anyusername12131 · **Reply #1 on:** Jun 25, 2018

Answer to Question 1

ANS: C
Patients with b-thalassemia major have a severe anemia; many of their clinical problems are related to this anemia. Giving the patient massive red cell transfusion therapy can ameliorate some of these clinical problems. Unfortunately, a serious consequence of this is the build-up of iron in the body from all the transfused RBCs because the body has no mechanism for excreting iron.

Answer to Question 2

ANS: A
The relative differential is normal.