Author Question: What ethnic group most often has glucose-6-phosphate dehydrogenase (G6PD) A- in the United States? ... (Read 51 times)

hubes95 · **on:** Jun 25, 2018

What ethnic group most often has glucose-6-phosphate dehydrogenase (G6PD) A- in the United States?

a. Northern European male subjects
b. Asian American female subjects
c. African American female subjects
d. African American male subjects

Question 2

All of the following would be expected 1 year after a splenectomy on a patient with severe hereditary spherocytosis except:

a. Spherocytes on the blood film
b. Howell-Jolly bodies
c. Reticulocyte count of 10
d. Siderocytes

bigcheese9 · **Reply #1 on:** Jun 25, 2018

Answer to Question 1

ANS: D
In the United States, African American male subjects are the ethnic group that most commonly has G6PD A- deficiency. From 10 to 11 of these subjects carry this gene. The gene is X linked, so that female subjects are carriers and generally do not have clinical problems.

Answer to Question 2

ANS: C
After splenectomy, the anemia is usually corrected and reticulocyte counts return to high normal. However, the consequences of splenectomy, done for whatever reason, are the appearance of Howell-Jolly bodies, siderocytes, and target cells in red cells. Spherocytes will still be observable in hereditary spherocytosis.