The sites of active red marrow differ for adults and young ...

[khang]

The sites of active red marrow differ for adults and young children. Which one site is active in children but not in adults?
 
  a. Proximal end of the long bones
  b. Skull
  c. Distal ends of the long bones
  d. Pelvis

Question 2

Which of the following is least helpful in evaluating bone marrow findings?
 
  a. Differential performed on the aspirate
  b. Clinical findings
  c. Laboratory data from chemistry, immunology, and microbiology
  d. Examination of peripheral blood

[Kedrick2014]

Answer to Question 1

ANS: C
Red marrow is found in all the bones in children, including the distal ends of the long bones. It also initially has no fat. As the child grows and the bones lengthen and enlarge, all the available marrow space is no longer needed for blood cell production. The marrow space no longer needed becomes inactive and fatty (yellow marrow). It can be converted to active marrow if the demand for blood cells becomes excessive. Red marrow in an adult is composed of both blood-producing cells and fat in a roughly 1:1 ratio.

Answer to Question 2

ANS: C
All clinical laboratory findings should be interpreted in light of the clinical findings (physical examination and history). It is also important to compare the bone marrow findings from the differential with what is in peripheral blood, because blood cells are derived from the bone marrow. In general, laboratory data from other sections of the laboratory are not needed; however, this is not the case when working up patients for certain diseases (e.g., protein electrophoresis in a patient suspected to have multiple myeloma).

[khang]

Thanks for the timely response, appreciate it

[robbielu01]

Excellent