Author Question: A patient is admitted to the local hospital with a pulmonary embolus. He was unconscious when ... (Read 62 times)

dalyningkenk · **on:** Jun 25, 2018

A patient is admitted to the local hospital with a pulmonary embolus. He was unconscious when admitted to the emergency department. Ultrasound revealed a large clot in the patient's saphenous vein.

Thrombolytic therapy is administered, and eventually the patient's condition stabilizes. Laboratory tests are performed at hospital admission; their results follow:

PT: 15.5 sec
INR: 2.85
APTT: 76 sec
Protein C antigen: 14
Protein C functional activity: 18
Molecular studies: FV-R506Q present

Based on this information, what is the most probable diagnosis for this patient?
a. PC deficiency and factor V deficiency
b. PS deficiency and factor V deficiency
c. APCR and PC deficiency
d. HC-II deficiency

Question 2

What are the physiological processes involved in hypercoagulability?

What will be an ideal response?

trampas · **Reply #1 on:** Jun 25, 2018

Answer to Question 1

Correct Answer: C

Answer to Question 2

Answer: Hypercoagulability occurs when there is an imbalance between procoagulants (increase) or anticoagulants (decrease).
The chief thrombogenic agents that are altered in hypercoagulable conditions are the vascular endothelium, platelets, and coagulation proteins.