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Author Question: A procedure used to decrease the potential for GVHD in an allogeneic transplant is: a. Freeze ... (Read 26 times)

charchew

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on: Jun 25, 2018
A procedure used to decrease the potential for GVHD in an allogeneic transplant is:
 
  a. Freeze thaw to kill lymphocytes
  b. Activation of CD4 cells and suppression of CD8 cells.
  c. Purge of CD8 lymphocytes
  d. Apheresis

Question 2

Compare and contrast the collection of umbilical cord stem cells for transplantation and that of allogeneic stem cells for transplantation.
 
  What will be an ideal response?


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tjayeee

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Reply #1 on: Jun 25, 2018
Answer to Question 1

Correct Answer: C

Answer to Question 2

Answer: Umbilical cord stem cell transplantation.
Umbilical cord stem cells
 Are abundantly available.
 Specimen collection poses no risk to mother and infant.
 Can be frozen
 Have a low risk of viral contamination
 Dos not have mature T cells, so risk of GVH is low
 Generally have a low total number of stem cells for an adult transplant patient
 Can reduce the GVL effect
 Have only one unit available for each procedure
Allogeneic stem cells:
 Are adequate for transplant in adults
 Provide multiple units available for each procedure
 Compatibility testing essential
 Cryopreservation possible


charchew

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Reply 2 on: Jun 25, 2018
Thanks for the timely response, appreciate it

scottmt

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Reply 3 on: Yesterday
:D TYSM

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