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Author Question: Explain how EPO regulates RBC production. What will be an ideal ... (Read 73 times)

fnuegbu

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on: Jun 25, 2018
Explain how EPO regulates RBC production.
 
  What will be an ideal response?

Question 2

Which of the following molecules is a senescence signal when it is exposed on the outer leaflet of the erythrocyte?
 
  a. Band 3
  b. Ankyrin
  c. Phosphatidylethanol amine (PE)
  d. Phosphatidylserine (PS)


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essyface1

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Reply #1 on: Jun 25, 2018
Answer to Question 1

Answer: Erythropoiesis is governed by a negative feedback mechanism centered on hypoxic conditions. Hypoxia stimulates synthesis of EPO by the kidney. When erythropoiesis is sufficient to correct the hypoxia, the negative feedback is shut off. This is done by downregulating kidney synthesis of EPO.

Answer to Question 2

Correct Answer: D


fnuegbu

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Reply 2 on: Jun 25, 2018
Thanks for the timely response, appreciate it

essyface1

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Reply 3 on: Yesterday
Great answer, keep it coming :)

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