Author Question: List and explain the function of the cells in the bone marrow stroma. What will be an ideal ... (Read 65 times)

jlmhmf · **on:** Jun 25, 2018

List and explain the function of the cells in the bone marrow stroma.

What will be an ideal response?

Question 2

List four causes of a hyperplastic marrow.

What will be an ideal response?

Ksanderson1296 · **Reply #1 on:** Jun 25, 2018

Answer to Question 1

Answer: The bone marrow stroma provides a supportive microenvironment for developing hematopoietic cells. It forms a three-dimensional scaffold for support and adhesion of developing cells. It also facilitates cell-cell interactions by providing essential cytokines to the hematopoietic dividing cells.

Answer to Question 2

Answer:
a. Acute blood loss causes transient erythrocytosis.
b. Increased proliferation of monoclonal or polyclonal populations of hematopoietic cells, such as leukemia
c. Ineffective hematopoiesis. Example: Vitamin B12 deficiency.
d. Abnormal stimulation or abnormal response to stimulation of stem cells/progenitors from internal or external stimulants.