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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.
Multiple sclerosis is a condition wherein the body's nervous system is weakened by an autoimmune reaction that attacks the myelin sheaths of neurons.
Drug-induced pharmacodynamic effects manifested in older adults include drug-induced renal toxicity, which can be a major factor when these adults are experiencing other kidney problems.
Asthma is the most common chronic childhood disease in the world. Most children who develop asthma have symptoms before they are 5 years old.