A woman affected with an X-linked recessive disorder: A. Has ...

[rayancarla1]

A woman affected with an X-linked recessive disorder:
 
  A. Has one X chromosome affected by the mutation
  B. Will transmit the disorder to all of her children
  C. Will transmit the disorder to all of her sons
  D. Will not transmit the mutation to any of her daughters

Question 2

In creating your female patient's pedigree, you note that she and both of her sisters were affected by the same genetic disorder.
 
  Although neither of her parents had indications of the disorder, her paternal grandmother and her paternal grandmother's two sisters were affected by the same condition. This pattern suggests:
  A. Autosomal dominant disorder
  B. Chromosomal disorder
  C. Mitochondrial DNA disorder
  D. X-linked dominant disorder

[tdewitt]

Answer to Question 1

ANS: C
An X-linked recessive disorder means that in a woman, both X chromosomes must have the mutation if she is to be affected. Because males have only one copy of the X chromosome, they will be affected if their X chromosome carries the mutation.

Answer to Question 2

ANS: D
A man with an X-linked dominant disorder will transmit the mutation to 100 of his daughters (they receive his X chromosome) and none of his sons (they receive his Y chromosome). The pedigree of a family with an X-linked dominant disorder would reveal all the daughters and none of the sons affected with the disorder if the father has an X-linked disorder.