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Though Candida and Aspergillus species are the most common fungal pathogens causing invasive fungal disease in the immunocompromised, infections due to previously uncommon hyaline and dematiaceous filamentous fungi are occurring more often today. Rare fungal infections, once accurately diagnosed, may require surgical debridement, immunotherapy, and newer antifungals used singly or in combination with older antifungals, on a case-by-case basis.
The FDA recognizes 118 routes of administration.
In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.
Increased intake of vitamin D has been shown to reduce fractures up to 25% in older people.
Aspirin is the most widely used drug in the world. It has even been recognized as such by the Guinness Book of World Records.

