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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
Drying your hands with a paper towel will reduce the bacterial count on your hands by 45–60%.
Before a vaccine is licensed in the USA, the Food and Drug Administration (FDA) reviews it for safety and effectiveness. The CDC then reviews all studies again, as well as the American Academy of Pediatrics and the American Academy of Family Physicians. Every lot of vaccine is tested before administration to the public, and the FDA regularly inspects vaccine manufacturers' facilities.
Since 1988, the CDC has reported a 99% reduction in bacterial meningitis caused by Haemophilus influenzae, due to the introduction of the vaccine against it.
A seasonal flu vaccine is the best way to reduce the chances you will get seasonal influenza and spread it to others.