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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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Approximately 500,000 babies are born each year in the United States to teenage mothers.
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Cyanide works by making the human body unable to use oxygen.
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In women, pharmacodynamic differences include increased sensitivity to (and increased effectiveness of) beta-blockers, opioids, selective serotonin reuptake inhibitors, and typical antipsychotics.
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Pope Sylvester II tried to introduce Arabic numbers into Europe between the years 999 and 1003, but their use did not catch on for a few more centuries, and Roman numerals continued to be the primary number system.