In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.
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The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.
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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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Intradermal injections are somewhat difficult to correctly administer because the skin layers are so thin that it is easy to accidentally punch through to the deeper subcutaneous layer.
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Interferon was scarce and expensive until 1980, when the interferon gene was inserted into bacteria using recombinant DNA technology, allowing for mass cultivation and purification from bacterial cultures.