The nurse is reviewing the characteristics of autosomal dominant ...

[torybrooks]

The nurse is reviewing the characteristics of autosomal dominant inheritance. Which are true about these characteristics? (Select all that apply.)
 
  a. A carrier state exists.
  b. The phenotype appears in consecutive generations.
  c. Males and females are equally likely to be affected.
  d. Parents who have affected children are usually asymptomatic.
  e. Children of an affected parent have a 50 chance of being affected.

Question 2

Which can be directly attributed to a single-gene disorder? (Select all that apply.)
 
  a. Cleft lip
  b. Cystic fibrosis
  c. Turner syndrome
  d. Klinefelter syndrome
  e. Neurofibromatosis

[Koolkid240]

Answer to Question 1

ANS: B, C, E
Characteristics of autosomal dominant inheritance include the phenotype appears in consecutive generations, males and females are equally affected, and children of an affected parent have a 50 chance of being affected. A carrier state and parents who have affected children are usually asymptomatic are characteristic of autosomal recessive inheritance.

Answer to Question 2

ANS: B, E
Cystic fibrosis is a single-gene disorder inherited as an autosomal recessive trait, and neurofibromatosis is a single-gene disorder inherited as an autosomal dominant trait. Cleft lip is classified as a multifactorial disorder in which a genetic susceptibility and appropriate environment appear to play important roles. Turner and Klinefelter syndromes are disorders of sex chromosome number.