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Coca-Cola originally used coca leaves and caffeine from the African kola nut. It was advertised as a therapeutic agent and "pickerupper." Eventually, its formulation was changed, and the coca leaves were removed because of the effects of regulation on cocaine-related products.
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There are over 65,000 known species of protozoa. About 10,000 species are parasitic.
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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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The term pharmacology is derived from the Greek words pharmakon("claim, medicine, poison, or remedy") and logos ("study").