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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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In the United States, an estimated 50 million unnecessary antibiotics are prescribed for viral respiratory infections.
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In 1835 it was discovered that a disease of silkworms known as muscardine could be transferred from one silkworm to another, and was caused by a fungus.
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The modern decimal position system was the invention of the Hindus (around 800 AD), involving the placing of numerals to indicate their value (units, tens, hundreds, and so on).
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According to the FDA, adverse drug events harmed or killed approximately 1,200,000 people in the United States in the year 2015.