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In 1864, the first barbiturate (barbituric acid) was synthesized.
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The Romans did not use numerals to indicate fractions but instead used words to indicate parts of a whole.
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Blood is approximately twice as thick as water because of the cells and other components found in it.
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The first war in which wide-scale use of anesthetics occurred was the Civil War, and 80% of all wounds were in the extremities.
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Oliver Wendell Holmes is credited with introducing the words "anesthesia" and "anesthetic" into the English language in 1846.