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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Malaria was not eliminated in the United States until 1951. The term eliminated means that no new cases arise in a country for 3 years.
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As the western states of America were settled, pioneers often had to drink rancid water from ponds and other sources. This often resulted in chronic diarrhea, causing many cases of dehydration and death that could have been avoided if clean water had been available.
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The human body produces and destroys 15 million blood cells every second.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.