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It is believed that the Incas used anesthesia. Evidence supports the theory that shamans chewed cocoa leaves and drilled holes into the heads of patients (letting evil spirits escape), spitting into the wounds they made. The mixture of cocaine, saliva, and resin numbed the site enough to allow hours of drilling.
Opium has influenced much of the world's most popular literature. The following authors were all opium users, of varying degrees: Lewis Carroll, Charles, Dickens, Arthur Conan Doyle, and Oscar Wilde.
The immune system needs 9.5 hours of sleep in total darkness to recharge completely.
Excessive alcohol use costs the country approximately $235 billion every year.
Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
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