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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
The people with the highest levels of LDL are Mexican American males and non-Hispanic black females.
Giardia is one of the most common intestinal parasites worldwide, and infects up to 20% of the world population, mostly in poorer countries with inadequate sanitation. Infections are most common in children, though chronic Giardia is more common in adults.
Aspirin is the most widely used drug in the world. It has even been recognized as such by the Guinness Book of World Records.
More than 150,000 Americans killed by cardiovascular disease are younger than the age of 65 years.