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Women are 50% to 75% more likely than men to experience an adverse drug reaction.
Pope Sylvester II tried to introduce Arabic numbers into Europe between the years 999 and 1003, but their use did not catch on for a few more centuries, and Roman numerals continued to be the primary number system.
More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.
Historic treatments for rheumatoid arthritis have included gold salts, acupuncture, a diet consisting of apples or rhubarb, nutmeg, nettles, bee venom, bracelets made of copper, prayer, rest, tooth extractions, fasting, honey, vitamins, insulin, snow collected on Christmas, magnets, and electric convulsion therapy.