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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.
More than 30% of American adults, and about 12% of children utilize health care approaches that were developed outside of conventional medicine.
Aspirin is the most widely used drug in the world. It has even been recognized as such by the Guinness Book of World Records.