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Essential fatty acids have been shown to be effective against ulcers, asthma, dental cavities, and skin disorders such as acne.
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Thyroid conditions cause a higher risk of fibromyalgia and chronic fatigue syndrome.
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In 1885, the Lloyd Manufacturing Company of Albany, New York, promoted and sold "Cocaine Toothache Drops" at 15 cents per bottle! In 1914, the Harrison Narcotic Act brought the sale and distribution of this drug under federal control.
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In 2010, opiate painkllers, such as morphine, OxyContin®, and Vicodin®, were tied to almost 60% of drug overdose deaths.
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Throughout history, plants containing cardiac steroids have been used as heart drugs and as poisons (e.g., in arrows used in combat), emetics, and diuretics.