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Coca-Cola originally used coca leaves and caffeine from the African kola nut. It was advertised as a therapeutic agent and "pickerupper." Eventually, its formulation was changed, and the coca leaves were removed because of the effects of regulation on cocaine-related products.
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It is difficult to obtain enough calcium without consuming milk or other dairy foods.
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The Romans did not use numerals to indicate fractions but instead used words to indicate parts of a whole.
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Fungal nail infections account for up to 30% of all skin infections. They affect 5% of the general population—mostly people over the age of 70.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.