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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
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Of the estimated 2 million heroin users in the United States, 600,000–800,000 are considered hardcore addicts. Heroin addiction is considered to be one of the hardest addictions to recover from.
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Patients who have been on total parenteral nutrition for more than a few days may need to have foods gradually reintroduced to give the digestive tract time to start working again.
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The U.S. Preventive Services Task Force recommends that all women age 65 years of age or older should be screened with bone densitometry.
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Asthma cases in Americans are about 75% higher today than they were in 1980.

