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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
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Malaria was not eliminated in the United States until 1951. The term eliminated means that no new cases arise in a country for 3 years.
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By definition, when a medication is administered intravenously, its bioavailability is 100%.
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The average adult has about 21 square feet of skin.
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It is believed that the Incas used anesthesia. Evidence supports the theory that shamans chewed cocoa leaves and drilled holes into the heads of patients (letting evil spirits escape), spitting into the wounds they made. The mixture of cocaine, saliva, and resin numbed the site enough to allow hours of drilling.