Order: Zofran (ondansetron HCl) 0.15mg/kg IVPB 30 minutes before ...

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Order: Zofran (ondansetron HCl) 0.15mg/kg IVPB 30 minutes before chemotherapy. The label on the vial reads 2 mg/mL, and the manufacturer's directions states to dilute in 50 mL D5W and infuse in 15 minutes.
 
  Calculate the rate of flow in drops per minute for a patient who weighs 55 kilograms. The drop factor is 10 gtt/mL. 1. 216 gtt/min
  2. 72 gtt/min
  3. 36 gtt/min
  4. 14 gtt/min

Question 2

Order: DTIC-Dome (dacarbazine) 250 mg/m IV for five days. The label on the vial reads 100 mg, and the manufacturer's directions states to reconstitute with 9.
 
  9 mL of sterile water for injection, yielding a strength of 10 mg/mL, further dilute in 250 mL of D5W, and infuse over 60 minutes. Calculate the rate of flow in milliliters per hour for a patient who weighs 92 kilograms and is 183 centimeters tall. 1. 250 mL/h
  2. 304 mL/h
  3. 367 mL/h
  4. 540 mL/h

[frankwu0507]

Answer to Question 1

3

Global Rationale: 50 + 4 = 54 mL; 54 mL/0.25 h = 216 mL/h.

Answer to Question 2

2

Global Rationale: 2.16 m2  250 = 540 mg; 54 mL + 250 mL = 304 mL.

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Gracias!

[Joy Chen]

TYSM