Normal hemoglobin is a tetramer, consisting of two molecules of β hemoglobin and two molecules of α hemoglobin. In sickle-cell disease, as a result of a single amino acid change, the mutant hemoglobin tetramers associate with each other and assemble into large fibers. Based on this information alone, we can conclude that sickle-cell hemoglobin exhibits
A) altered primary structure.
B) altered secondary structure.
C) altered tertiary structure.
D) altered quaternary structure.
E) altered primary structure and altered quaternary structure; the secondary and tertiary structures may or may not be altered.
Differences in oxygen-hemoglobin dissociation curves under different physiological conditions and am
(A) Normal glomerulus and (B) acute glomerulonephritis.
Neutrophils in a normal blood smear.
Normal red blood cells (round) and sickled red blood cells
Distribution of dystrophin in muscle cells. (a) In normal muscle cells, all the dystrophin is locate
Brain metabolism in a schizophrenic individual (left) and a normal individual (right). These scans o