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In 1885, the Lloyd Manufacturing Company of Albany, New York, promoted and sold "Cocaine Toothache Drops" at 15 cents per bottle! In 1914, the Harrison Narcotic Act brought the sale and distribution of this drug under federal control.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
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The Romans did not use numerals to indicate fractions but instead used words to indicate parts of a whole.
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Between 1999 and 2012, American adults with high total cholesterol decreased from 18.3% to 12.9%