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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
On average, the stomach produces 2 L of hydrochloric acid per day.
More than 4.4billion prescriptions were dispensed within the United States in 2016.
Serum cholesterol testing in adults is recommended every 1 to 5 years. People with diabetes and a family history of high cholesterol should be tested even more frequently.
According to the FDA, adverse drug events harmed or killed approximately 1,200,000 people in the United States in the year 2015.