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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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The first oncogene was discovered in 1970 and was termed SRC (pronounced "SARK").
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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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The B-complex vitamins and vitamin C are not stored in the body and must be replaced each day.