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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
Urine turns bright yellow if larger than normal amounts of certain substances are consumed; one of these substances is asparagus.
In 1864, the first barbiturate (barbituric acid) was synthesized.
Egg cells are about the size of a grain of sand. They are formed inside of a female's ovaries before she is even born.
Oliver Wendell Holmes is credited with introducing the words "anesthesia" and "anesthetic" into the English language in 1846.