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In women, pharmacodynamic differences include increased sensitivity to (and increased effectiveness of) beta-blockers, opioids, selective serotonin reuptake inhibitors, and typical antipsychotics.
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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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People with high total cholesterol have about two times the risk for heart disease as people with ideal levels.
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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
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Malaria was not eliminated in the United States until 1951. The term eliminated means that no new cases arise in a country for 3 years.