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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
Cyanide works by making the human body unable to use oxygen.
Warfarin was developed as a consequence of the study of a strange bleeding disorder that suddenly occurred in cattle on the northern prairies of the United States in the early 1900s.
After 5 years of being diagnosed with rheumatoid arthritis, one every three patients will no longer be able to work.
Cancer has been around as long as humankind, but only in the second half of the twentieth century did the number of cancer cases explode.