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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.
On average, someone in the United States has a stroke about every 40 seconds. This is about 795,000 people per year.
In 1844, Charles Goodyear obtained the first patent for a rubber condom.
After 5 years of being diagnosed with rheumatoid arthritis, one every three patients will no longer be able to work.