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The FDA recognizes 118 routes of administration.
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Throughout history, plants containing cardiac steroids have been used as heart drugs and as poisons (e.g., in arrows used in combat), emetics, and diuretics.
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Pope Sylvester II tried to introduce Arabic numbers into Europe between the years 999 and 1003, but their use did not catch on for a few more centuries, and Roman numerals continued to be the primary number system.
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It is difficult to obtain enough calcium without consuming milk or other dairy foods.
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Increased intake of vitamin D has been shown to reduce fractures up to 25% in older people.