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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
Malaria was not eliminated in the United States until 1951. The term eliminated means that no new cases arise in a country for 3 years.
There are more nerve cells in one human brain than there are stars in the Milky Way.
The toxic levels for lithium carbonate are close to the therapeutic levels. Signs of toxicity include fine hand tremor, polyuria, mild thirst, nausea, general discomfort, diarrhea, vomiting, drowsiness, muscular weakness, lack of coordination, ataxia, giddiness, tinnitus, and blurred vision.
The U.S. Preventive Services Task Force recommends that all women age 65 years of age or older should be screened with bone densitometry.