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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
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This year, an estimated 1.4 million Americans will have a new or recurrent heart attack.
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Illicit drug use costs the United States approximately $181 billion every year.
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Though the United States has largely rejected the metric system, it is used for currency, as in 100 pennies = 1 dollar. Previously, the British currency system was used, with measurements such as 12 pence to the shilling, and 20 shillings to the pound.
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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.