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Medication errors are more common among seriously ill patients than with those with minor conditions.
Sildenafil (Viagra®) has two actions that may be of consequence in patients with heart disease. It can lower the blood pressure, and it can interact with nitrates. It should never be used in patients who are taking nitrates.
About 60% of newborn infants in the United States are jaundiced; that is, they look yellow. Kernicterus is a form of brain damage caused by excessive jaundice. When babies begin to be affected by excessive jaundice and begin to have brain damage, they become excessively lethargic.
In 1864, the first barbiturate (barbituric acid) was synthesized.
More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.

