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In the United States, there is a birth every 8 seconds, according to the U.S. Census Bureau's Population Clock.
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Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.
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In 1886, William Bates reported on the discovery of a substance produced by the adrenal gland that turned out to be epinephrine (adrenaline). In 1904, this drug was first artificially synthesized by Friedrich Stolz.
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By definition, when a medication is administered intravenously, its bioavailability is 100%.
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There are 60,000 miles of blood vessels in every adult human.