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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
When intravenous medications are involved in adverse drug events, their harmful effects may occur more rapidly, and be more severe than errors with oral medications. This is due to the direct administration into the bloodstream.
By definition, when a medication is administered intravenously, its bioavailability is 100%.
Hyperthyroidism leads to an increased rate of metabolism and affects about 1% of women but only 0.1% of men. For most people, this increased metabolic rate causes the thyroid gland to become enlarged (known as a goiter).