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Throughout history, plants containing cardiac steroids have been used as heart drugs and as poisons (e.g., in arrows used in combat), emetics, and diuretics.
The first war in which wide-scale use of anesthetics occurred was the Civil War, and 80% of all wounds were in the extremities.
Giardia is one of the most common intestinal parasites worldwide, and infects up to 20% of the world population, mostly in poorer countries with inadequate sanitation. Infections are most common in children, though chronic Giardia is more common in adults.
Aspirin is the most widely used drug in the world. It has even been recognized as such by the Guinness Book of World Records.
For pediatric patients, intravenous fluids are the most commonly cited products involved in medication errors that are reported to the USP.